In their last outing Leyton orient beat the Cobblers 3-0. This time around Leyton Orient will face Northampton at home, where they haven't yet gained a win this season.
Mauro Milanese knows he has a tough task ahead with the pressure on his side to do well in the competition. Many suggest that with team confidence waning Northampton have the chance to cause a big upset.
It's expected that Northampton Manager Chris Wilder will make changes to his starting line-up to combat the threat posed by Orient.
Whoever, wins the match should produce exciting viewing. Do you believe the Cobblers can pull off an upset tomorrow?